Air kills cartridges?

Do vintage cartridges deteriorate in performance by virtue of being exposed to air? I have heard that the only way to preserve their performance is to pack them in some chemical solution. Any comment would be appreciated.
If anyone was advocating a storage medium, it would probably be sealed in a gas-tight container filled with an inert gas like nitrogen. This could most easily be done at home using one of those wine preservative aerosol sprays that are likely mostly nitrogen. I have no idea how effective this is, but if you are planning on storing a cart for a long time it couldn't hurt and would be pretty cheap.
Felt like I walked into the wrong classroom...I have had a Genesis 2000 for maybe 10+ years with very low hours and just recently put it back on to play. So the question I started out some weeks back was "should I keep using the Genesis (but getting a SUP or headamp) or simply move to HOMC?" Genesis sounds great, BTW.
Sic transit gloria mundi! No matter if humans, nations, planets, cartridges.....
don't know what you just said but if "sic" has anything to do with "sick" I'd say you're not far off. ;-)