Best floorstanders under $1000 new or used

That's a big room, and will need a big speaker and some power to fill it. You need to tell us the amp you plan on using, the type of music, and the source.

A bit above your budget there are Epos ES30s on audiogon. These are great speakers. Stretch to them if you can and I think you'll keep them forever.

The rega floorstanders have a reputation for a balanced non-bright sound, but I have never heard them personally.

I once demod some B&W DM603s, and they have a really BIG sound, that would fill a large room, but I'm concerned that the metal dome tweeter might be a little bright for your tastes. They were a lot of fun though, particularly on rock music.

Maggie MG-12

Thanks for the ideas. Some of the integrated's that I'm looking at are a McIntosh MA6450 or MA6500, MF X150, or NAD 372 and the source is an entry level NAD 521BEE (to be upgraded eventually.)

What types of music do you listen to ? Do you want to be able to play air-guitar to AC/DC or bathe in the sound of a string quartet ? (I do both ... but finding speakers that do it all is tricky and/or expensive).