Best speakers for compressed audio

I know that combining real sound quality and mp3's is a contradiction however I'm sure some solutions are better than others. My home system comprises of Linn speakers (in fact I have three pairs), a NAD pre-amp, Rotel power amp and Rega CD player. At work I have a 320 gig hard drive filled with mp3 and flac music files. I recently purchased a pair of Audioengine A5's which sound great but get interference from the office network. I would welcome suggestions as to how to optimize the sound from compressed audio files as the source. Thanks!
Speakers aren't the answer. The only solution there would be to buy something with really low resolution so you can't hear how lousy the compressed file sounds.

One option that some people hold in high regard is the BBE Sound Restoration System --

Another option would be to switch to very warm tube amplification or insert a tube buffer stage between your hard drive or source and your preamp or amp.
Active speaker systems like Audioengines 5s and Blue Sky Monitors (EXO) handle compressed files wonderfully.

If you wish to go passive, I can also recommend the
Fatman iTube amp system out of the UK, tied to smaller monitors like the Paradigm Atoms or the PSB Alphas,
Michael try a power conditioner or new AC power cord if your getting interface. Then look into DAC (BenchMark or Bel Canto) if the hard drive has USB output. The DAC will improve Flac sound and mps (depending on the source) and the filter will clean-up the source noise.

Audience Adept Response aR1p $495

BenchMark 1 $1275