UPDATE: the ten second delay was my bad! Somehow I had set the resync delay to 10000 ms instead of 1000 ms. My wifi is just fine, but thank you, Jeff, for the comprehensive troubleshooting guide.
I have a Nano hooked up with a USB connection to my MC-53 (DA2). It sounds very good - at least as good at the Eversolo A6. To @jbuhl's question, the Nano was found by Roon and incorporated nicely. I still get a resync clipping the first half second or so of songs - I think that's just a problem of McIntosh's DAC that I have to live with.
I also played the Nano through the RCA connection and it sounds ok, but the Eversolo through XLR sounds better. That could simply be the cables, but I think the Bluesound DAC is the weakest of the three.
Anyway, back to the op's question, the Nano plays just fine with Roon.