Headphone DAC/Preamps

I am putting a system together for headphone listening AWAY from my main listening room -- hopefully wired through CAT6 cable). I need a DAC/Headphone amp and Headphones. I have noticed that some DAC/Headphone amps use "mini" plug jacks for their headphone out jacks. Is there any disadvantage between those and a standard 1/4 inch jack?

Does anyone have any hands-on experience to recommend a USB DAC/HEadphone amp (with pre-amp output also -- in case I want to output to an amp and speakers at a LATER DATe)?
I use an older Nuforce HDP dac/headphone amp. It's an older piece but I love it. It has the larger jack which suits me as I use Sennheiser HD-650 headphones. I would expect using headphones which have the same size plug as the jack on the amp would be advantageous because you eliminate an extra connection.
BTW, what is your price range?

I can't say positively there is any significant difference between balanced 1/4" & "mini" jack. That's why adapters are made. Buy both & post results.
P.S. I really like the Schiit Bifrost Multibit, Valhalla, HD650 route. This way you get a great headphone amp, a great dac (that's upgradeable as not to be obsolete) and the headphone amp has pre out so later on you can use it as a preamp (until you can upgrade to a dedicated preamp).

In my opinion this is the best way to go as far as sound quality, and flexibility for your future plans as well!