Jim, I highly, highly doubt it could ever damage the amps: there's just not enough power coming out of a preamp to do damage. Perhaps a really terribly designed preamp might fail.
To comment on whether the sound might change I'd have to know the output impedance of the pre, the input impedance of a single power amp, and the capacitance and resistance of the interconnect.
In most cases, with an active preamp, I highly doubt it would affect the sound. With a passive preamp, and/or power amps with input impedances under 10k ohms it might lose dynamics and roll off the high frequencies, but really you'd have to try it.