I have an account at a local UPS Store and they recommend shipping anything of value or fragile via overnight and/or 2nd day rather than regular ground for the simple reason that a regular ground package is handled and loaded/unloaded, etc. much more than a overnight or 2nd day package. Reportedly, the average package on a coast to coast trip may be handled by as many as 100 workers, whereas that number reporteldy drops to about 15 workers when sent overnight/2nd day.
As to the choice of FedEx or UPS, I have never (knock on wood) had a damaged delivery with either and I've shipped a LOT of stuff over the years. However, I usually ship UPS for the simple reason that the proprietor of another local shipping store I sometimes use that services both FedEx and UPS claims that in more than 5 years he has never had FedEx pay a damage claim, whereas UPS pays claims regularly (although they may make you jump through hoops). Apparently, FedEx uses a third party claims handler whereas UPS handles claims in house. Again, I have no personal experience here so YMMV, etc.