My tonearm, a Morch DP-8, mounted on an Amazon Reference TT, has a removable arm wand which allows for quickly switching from stereo to a dedicated Mono cartridge without having to make any adjustments.
I went full out with a dedicated Mono cartridge set up to play Mono pressings, primarily RCA Shaded Dog classical records from the '50s and '60s, which are very well recorded.
Comparing the sound of the pure Mono set-up with just playing the Mono records through the Stereo set-up did not, in my opinion, disclose any clear advantage of the Mono over the Stereo.
This may be because the Mono cartridge was not competitive with the much more expensive LOMC cartridge employed in the stereo set-up, although I was using a highly regarded Mono cartridge at the time.
Bear in mind the sound was different between the two, because of the employment of different sounding cartridges. The Mono rig sounded a little more robust dynamically, but the Stereo rig was more detailed and for reasons I cannot explain, seemed to have a wider soundstage, almost mimicking a Stereo effect.
My conclusion, for the limited times I listen to Mono recordings, the expense and hassle of having a dedicated Mono set-up was not worth the added expense for any perceived sonic gain.
These comparisons were done through a Nagra phono preamp, Elekit SET amplifier and Avantgarde Trio speakers. That is my experience for what it is worth.