Turn off ALL room correction and set your tone controls flat and center the balance.
Take your phone and check the SPL of the speakers first. Be as accurate as you can. IF the SPL is correct with tone burst, not music, turn around and see if the same thing happens. If it swaps sides it's your ears, if it stays on the same side it's usually an acoustic anomaly of the room. Don't put it past an actual gear/cabling or speaker issue. I would just make sure it wasn't me or the gear/cabling.
Gear swap cables.
Ears, that one is up to you.
Acoustic goofs.. Good Luck!! 50% of the actual sound quality IS room acoustics, start there first.
Regards