Usa, Think of changing tubes as comparible to changing components. It can make as much or more difference than the differences between CDP's or amps.
Lacking specific knowledge of the outcome of changing tubes in the '16' and what if any tonal differences you may appreciate, what I would suggest is that you do a bit of experimenting with some new production tubes to see what differences they might make. For example if you find that either JJ's, EI's, EH's, all of which have a different sonic signature, float you boat, you will have a basis for looking for some better NOS version with the same tonal signature, but might improve on things like high frequency clarity, bass response, etc.
Hope that helps a bit.
Lacking specific knowledge of the outcome of changing tubes in the '16' and what if any tonal differences you may appreciate, what I would suggest is that you do a bit of experimenting with some new production tubes to see what differences they might make. For example if you find that either JJ's, EI's, EH's, all of which have a different sonic signature, float you boat, you will have a basis for looking for some better NOS version with the same tonal signature, but might improve on things like high frequency clarity, bass response, etc.
Hope that helps a bit.