Let's say you have 10 fuses in your equipment, now you wish to start tuning, so you change the first fuse, you will buy 3 different choices, so 9 fuses remain original. You will finally select the fuse you like, after that, you will change the direction of that particular fuse to find the best result. Next you repeat this process with the second fuse, (remember, the first fuse may have to go back to the original, as that is another combination...) Now, after tens of thousands of combinations, many years later you may think to have found the best combination... However, sure enough by that time (or earlier) a new fuse will become available, and you have to start the process all over again. For those being into this, enjoy the "tuning" hobby. A similar process is needed for cable selection, after that the footers, outlets, contact cleaners, and many other variables where you can play with. It will be impossible to live long enough to try out all the variables....
Summarizing we can say that some people are in this hobby because of the tuning involved, others are in it to enjoy the music, accepting that yes, if they spent many years of tuning, the result would be slightly better than with the original equipment....(a smaller group of "audiophiles" even try to understand why it sounds different, develop their own theories, which provides entertainment as per the above).... Whichever way you like it, as long as you are happy, never mind.