My room is 23'x13.5' and my speakers are Coincident Total Eclipse II's. I spent 3 weeks listening to the standard version and loved it, but returned it because of the industrial look of the sub. Salk is building me a sub as we speak with a dyed maple burl in high gloss. It looks like gorgeous art, which matches better with my main speakers and my home. It should be ready in a month, so I haven't heard it yet.
I did notice that there was lots of vibration on the standard version, when I put my hand on top of it during moderate use. I believe that is the reason Salk focused his version on bolstering this area. Jim said that his upgrade reduces this so there is hardly any vibrations. Now whether this can be discerned from the listening chair, I can't say.
I found both the F110 and Rythmik F12G to be very tuneful and musical subs. The biggest difference was that the F12G had more output and easily reached depths that the F110 couldn't touch. I loved the auto EQ the F110 has, which the F12G doesn't. The F110 looks gorgeous, but also cost a lot more.
My bias is that I love bass. When I play the Eagles live cd or powerful classical music, I want it to sound realistic. I like to tune subs so that they don't draw attention to themselves, like you don't even know they are on, until you switch them off and then you can tell.