Raleigh is fast growing area. Very good for business, jobs... Not sure about Winston-Salem, but passing by I've noticed a lot of corporate and industrial properties which is IMHO a great sign. The bible belt is also broken I'd say around Winston-Salem and Triangle(Raleigh-Durham-Chapel Hill) and not anymore church is the only place of entertainment: cool clubs, restaurants, bars, performing arts venues where greatest and famous artists stop by with performances... Pretty much everything you can get in NYC or Twins in terms of living in large city. You can smell pot smoke next to night clubs and cops don't get crazy about busting onse using it. The longer I live there the more money I make, and the more positive things happening with only exception to summer which I hate here.
The summer is terrible -- sometimes month-worth of over 90F temperatures and upto 2-weeks worth of at or over 100F. Myrtle Beach is great escape from exsessive heat within 3...4.5hours. The rest of seasons great!