I have tried the dac direct route in my office system. In the office I am feeding Emotiva XPA 1 monoblocks which drive an older set of VanL quattros. I tried my Cary 200T Dac direct and the sound was Ok. I moved the 200T back to another system with a Cary preamp, well broken in Odessey Kismets monos, and highly Modified VanLs, the sound is phennominal (to my ears).
I have subsequently gone direct from an RME ADI DAC 2 FS into the Emotiva XPA 1s in my office and because of the myriad features of the RME it works extremely well direct to the monos and allows me to compensate for room irregularities in my office / Qi Gong studio. That said I will look down the line to introduce a little tube coloration into the office setup. As stated by others it is a matter of taste and system synergy. Each element: cables, wires, power all, add or detract from the overall effect.