It is the complex environment of what you speak. This is why USB and Ethernet cables are twisted pairs and shielded. The designers knew this. Partly for the spec of 11 feet. USB was not intended to exist in a vacuum.
Yes, I blame shortcomings on the end points not implementing good practice. In a $100 DAC, it is cost driven so some slack is given. But in a $500? Nope. $5,000? Pure incompetence.
I did loopback tests between free cables and correctly designed USB cables. Big difference and it shows up in a spectrum analyzer. Added an isolator, and presto, no problem. Two piles, good and bad. You can add a braided sheath and a fancy box, but it won't transfer bits any better.
Remember, it is not the digital waveform that matters. It is how it is detected, PE, NRZ, windowed, etc and then gated into a shift register to be accessed by the DSP section. Even DSD is re-generated. No place for magical properties to hide.
FWIW, I just ordered a D400es and it does NOT have a galvanic isolator. Bad design for that price point considering how much they spent on the cabinet. I will test both with an analyzer and my ears if ones needed in my cabinet. I pay attention to cable dress and common power so It probably is not. I have dead silence through my speakers with no active signal.