What are you trying to get out of it? Your center channel amp is overkill! If you have a HT receiver, use the HT receiver amp for HT, then use your good amps for 2ch. For HT it is very important that all speakers are timber matched, as sound goes around the room the tone is matched just as the volume/db should be. You also have REL subs? Why not just use them and not another one? Feel like you got all the gear and just want to use it, you can most likely get better sound using less, and making it simpler.
I have 2 separate systems, one for HT and one for 2ch. Neither does the other's job well. Will tell you when the HT is all setup correctly, it's awesome! Mine is better then most theaters.
5.1 is good, when you step up to 7.2.4 or something like that it becomes magical. You can hear a door shut in space, as well where the plane is coming from, how high, is is climbing or diving. It trips my dogs out all the time.