Are there guidlines to fix strange room acoustics?

For instance, if you're center image is off center can you fixit with moving just one speaker in, out, back, forward, more or less toe?

Also, what if bass is noticeably louder in one corner, and you can hear it from your listening chair and if you get up and stand in that corner, the bass is louder in that corner vs. the other corners. My listening room is set up equally on both sides, so I can't figure out for the life of me why the bass is collecting in one corner. I do have a few bass traps and have moved them all over and it doesn't change...

Should I try setting up my system with the center stage centered in a corner of the room? Should I just move it into the unfinished basement with exposed concrete floors and exposed plastic lined insulation? Theres plenty of room down there, but its very "alive" and echoey (is that even a word??).