I turn everything off except a Rel sub that's designed to be left on (no on/off switch anyway, and it's plugged into a different outlet...I unplug it when gone for days) as not much is happening until it gets a signal. Otherwise, having had gear work for MANY years without any issues from switching, I feel that more is likely to go wrong when electrons are running around my gear without adult supervision. I did have a hybrid guitar amp die from being on for a week once. I think it makes my gear appreciate me and perhaps look forward to seeing me as I can use my "godlike" powers to give it life. Am I insecure?