Most of you are generally going to use stranded wire conductors, so awg is not so critical. Of course, you'll have more capacitance issues with larger awg, so don't go super large like 16awg or larger. Instead, do multiple wires of 20+ awg if you want more wire for less resistance.
If you are using solid-core conductors, then I would say that 20awg is the largest you want to go unless you combine different awg. Anything larger than 20awg solid-core will start to lose high frequency response. In my extensive testing, 20awg is the sweet spot if you are only using one size. 22awg has excellent high frequency detail, but loss of bass power. 18awg starts to lose high frequency resolution.
The alternative is to combine different sizes. You could combine an 18awg and 21/22awg solid core wires. The smaller wire would provide the high frequency response and the larger wire carries the bass power. Audioquest speaker wire is designed just like this.
If you are using solid-core conductors, then I would say that 20awg is the largest you want to go unless you combine different awg. Anything larger than 20awg solid-core will start to lose high frequency response. In my extensive testing, 20awg is the sweet spot if you are only using one size. 22awg has excellent high frequency detail, but loss of bass power. 18awg starts to lose high frequency resolution.
The alternative is to combine different sizes. You could combine an 18awg and 21/22awg solid core wires. The smaller wire would provide the high frequency response and the larger wire carries the bass power. Audioquest speaker wire is designed just like this.