The advantage of the MacMini and MacBook and iMac is that all are very quiet. The latest Mac operating system requires 512mb just to run the OS, so you need a gig of ram to really run smoothly. MacBook should work just fine, but native hard drive space is a bit more limited. That should not matter if you are ripping your iTunes to an external drive. I don't know anything at all about the PS Audio DAC you mentioned. I can tell you that in general, and in my experience, you get more bang for you $ buying from small, passionate manufacturers who don't spend big bucks on advertising and frills (fancy packing and slick hardware). On your recap of what you need: yes, keyboard and mouse necessary with MacMini and come with iMac. None necessary with MacBook. USB cable needed if one does not come with DAC. Not sure what you need a second one for since the peripherals all have them included (keyboard and mouse). Analog RCA cables to go from DAC to amp. My suggestion was that you get two external hard drives, one of which is for backup of your music library. I don't suggest you store you music library on your native hard drive if it is of any significant size and you are ripping lossless files. It tends to grow, in my experience. I haven't owned any external hard drives that have been so noisy as to bother me when listening to music. I don't think you need a firewire drive for storing and accessing a music library via itunes, but that interface is certainly fast. iTunes and music streaming are not at all very demanding on a computer or memory. A USB interface hard drive, even USB 1.0 should be more than adequate on a Mac, especially if dedicated to music. I say that in light of someone's recommendation for firewire in that a Firewire drive is likely to cost more. It would be my preference too, but if I were trying to save money, I'd just look for a quiet USB drive. There are plenty out there.
On the question regarding a G5 tower and soundcards; it is my understanding that it is best to do all your conversions outside of the otherwise noisy electronic environment of your computer in a dedicated converter as opposed to using a sound card inside the computer. For your upsampling question regarding the G5 I'd suggest asking Steve Nugent at Empirical Audio, and or checking out what he has to offer in that realm. Definitely take the conversion outside the computer, though. This is not specific to the question of the original poster though - a USB DAC suits this purpose in your case.
Marco