I2s will give superior SQ to any other connection and using the Oppo Card above you'll get Native DSD into your DAC.
You could also get Native DSD over USB but the Oppo doesn't output USB.
I2S Card Upgrade - $220
This is add on card which extracts the I2S signal from OPPO's internal digital audio data and transfers via HDMI to the I2S input of DAC's such as the PS Audio DAC.
With this upgrade all digital audio signals, including SACD and DSD, can be transfered to the outside of the OPPO BD player (These signals can not be transmitted by a normal S/PDIF coaxial or optical output).
Currently, there are no standards for transmitting these I2S signals, but many manufacturers are following the PS Audio standard. This specification uses the HDMI terminal physically (not the HDMI transmission standard).
Currently PS Audio, Holo Audio and Javs DACs are confirmed for compatibility.