I quite agree with Drt. The ML 380S has more accurate control with the volume and there is more refinement in the various functions.
However, I currently have the X2.5 and I do like the sound which is closer to neutral. Aesthetics-wise I like the X2.5 better- the blue light grows on me- I think most ML designs look like large and sophisticated cable converters- too complicated looking. One important consideration to think about though is that the ML 380 like so many ML products have the power cord outlet in the bottom center of the unit (never made any sense to me- you most likely have to use the ML cords although I understand a few companies like PS Audio do make ones that fit). In my opinion with the Pass Labs, you have more options of tweaking especially when it comes to upgrading power cords. In addition, Pass Labs service is exemplary (one of the best in the business).
However, I currently have the X2.5 and I do like the sound which is closer to neutral. Aesthetics-wise I like the X2.5 better- the blue light grows on me- I think most ML designs look like large and sophisticated cable converters- too complicated looking. One important consideration to think about though is that the ML 380 like so many ML products have the power cord outlet in the bottom center of the unit (never made any sense to me- you most likely have to use the ML cords although I understand a few companies like PS Audio do make ones that fit). In my opinion with the Pass Labs, you have more options of tweaking especially when it comes to upgrading power cords. In addition, Pass Labs service is exemplary (one of the best in the business).