I agreed with VPI arm that no anti skating is by far the best option. However, for example my Reed 3Q arm, it does sound best with anti skating. With Air Tight PC-1 supreme, quite a lot of anti skating, with Lyra Atlas, a bit less but both sounded better than with no anti skating.
I don't think you can generalize this to every tonearm/cartridge combination.
I don't think you can generalize this to every tonearm/cartridge combination.