Think about it this way: the ideal speaker would be a one-way with no power draining, distorting crossover. Unfortunately no one has yet perfected a single driver that can coherently portray all the wavelengths we prefer. Regardless, it might be fun to get a couple of twin 12-inch Fender or Marshall guitar cabinets and blast away.
The most balanced, long-term listenable speakers I've ever heard have been two-ways: Dynaco A-25's; original Large Advents; and the ProAcs Sigs I use today. There's something right about a well done two-way that defies description.
Three or more drivers usually offer greater power handling capability. More radiating area can mean bigger, more dynamic sound. I had some KEF Uni-Q three-ways that propagated a bass wave so palpable you could almost see it. They were fun, went way loud without strain but ultimately were too analytical.
If you look at graphs of many multiple (two or more) driver, speaker systems' response curves there's often noticeable dips where one driver hands off to another. Designers exploit these and other peaks, dips and resonances to voice their entire systems. For me, two-ways are models of elegant engineering. Of course no speaker does everything right. Keep searching and you'll find successful, enjoyable designs of every kind.