combo systems can work well and are real world solutions for sure.
personally i have two separate system in 2 different rooms. a dedicated 2 channel room and separate home theater with Dolby Atmos 9.3.6 speaker configuration.
if you have questions about multi-channel speaker configuration here is the definitive guide for that from Trinnov, the experts.
https://drive.google.com/file/d/1qFpM5c9_n_0PU6EcW-J5qFvf4QDWqjg3/view