I've used JRiver, iTunes, FooBar and Media Monkey. They can all deliver bit-perfect digital stream to a DAC, with proper set-up (or in the case of iTunes, an add-on like Pure Music).
So it comes down to ease of use and learning curve, and what you are trying to accomplish with your music management.
For me, JRiver offers excellent flexibility for displaying your music collection in different ways. I use different "View" schemes for classical, jazz and popular music. For classical, the ability to "slice and dice" by composer, artist, soloist, orchestra, conductor, genre, period, style - is absolutely incredible (It does require lots of work to get the tagging correct in the database, but the public databases like AMG make this easier all the time). Anyway, I don't believe you can tag/display/search with that kind of flexibility with iTunes.
OTOH, if you only listen to popular music, and want to keep it simple, stick to iTunes.