Each method you mention could be the best or worst depending on what speakers, what cables, what jumpers if you don't biwire, what amplifier, your hearing, yada yada yada.
You can also biwire, etc, using a different type/brand of cable for the high and low frequency terminals.
If you don't biwire, definitely get rid of the stock jumpers they give you with the speakers. Most (not all) people who use jumpers, have more luck putting the cables to the high frequency terminals, with the jumpers going to the low frequency terminal. (Try it both ways.)
This should keep you busy for about a month or more!