It appears that only one person has actually addressed your original question. Responding to it, plus a few other things as follows:
1) It is likely your speakers causing the fatigue. The OM7 have an upward tilt in the higher frequencies and reviews them commented about them having some glare.
2) Your room could be contributing to the glare. I always suggest treating the first reflection points (free information on GIK Acoustics site and they will make recommendations for your room for free and have great products at good prices).
3) You need to decide what speaker type speaks to you. Your current speakers are a bipolar design. If you like the more diffuse sound they bring, a dipolar Magnepan may fill your need. My reluctance for you with a Magnapan is that your amp may not have enough power depending on your volume levels. The LRS is an amazing value and would leave a lot of money in your pocket. People tend to love or hate bipolar and dipolar speakers. They do some things well, others not so much. I have large Magnepans and love them, but that doesn’t make them correct for you.
4) Some have suggest horns. Horns have amazing dynamics but sacrifice in other areas. You have to listen to some (Klipsch being most he most common brand and well developed) and decide if they fit your likes. Again, they tend to be love it or hate them.
5) Monopolar dynamic speakers are the most common design. Different manufactures have different philosophies about what is most important in design and what they are willing to trade off (i.e. phase coherence, efficiency, bass extension, off axis response characteristics, cabinet design, tonal balance, etc.). Again, you have to pick what you find important. The Thiel you propose are great speakers, with my only concern being parts availability as Thiel is gone. The Vandersteen 2CE Sig 2 are another excellent suggestion, as are the suggestions of Ascent Acoustics and Salk Sound. The used suggestion of Aerials or Revels are also great.
6) I would not allocate money towards a subwoofer right now as some are suggesting. You indicate you have a Hsu subwoofer, and even their older Sonotube based subs (Like the 1220) were good sounding.