Great question. My first gut feeling is no but were you considering original C4's or the new MKII? I ask because the MKII sounds so much better at lower volumes when compared to the originals which might work. Like Pdreher mentioned the originals sound the best at higher listening levels. That being said I am assuming you would be placing the speakers on the short 15' wall.
I base this info on the fact I had origianl C1's and have since upgraded to the C1 Signature in Mocha. I also have a Rel B3 sub. Ideally if possible an in home demo would be way to go.