Yes, it matters.
All the bits have to be retrieved and transmitted accurately.
Then the bits comprising each sample have to be converted to the proper analog voltage level by the DAC at precisely the right time.
Variations in these two fundamental operations will affect sound quality to some extent.
The good news is the technology needed to do this reliably and within tolerances needed to produce good results, at least with CD redbook digital is becoming quite mature and is not radically expensive. Different devices will produce different results however and the differences are often audible.
All the bits have to be retrieved and transmitted accurately.
Then the bits comprising each sample have to be converted to the proper analog voltage level by the DAC at precisely the right time.
Variations in these two fundamental operations will affect sound quality to some extent.
The good news is the technology needed to do this reliably and within tolerances needed to produce good results, at least with CD redbook digital is becoming quite mature and is not radically expensive. Different devices will produce different results however and the differences are often audible.