Chadeffect:
Wayneker2176 answered your question much better than I could. I am gradually dipping my toes into computer audio, but am in no hurry. I figure time is on my side here, as there appear to be new digital software and connection breakthroughs fairly often. As the technology matures and standardizes, I may become more interested. For now, guess I'll just have to "make do".
FWIW - my re-worked Esoteric now has 20 2nd generation 32bit AKM DACs/side, fully differential, transformer coupled tube Class A output stage featuring the vintage E182CC tubes and Lundahl audio transformers. It also accepts up to 192KHz/24bit from external digital sources. The interface is Coaxial. I'm pretty happy, "making do". :-)