No problem. I am using two Raspberry Pi computers as end-points to my LAN. The main system gets the signal from my 7Tb server, into the Allo DigiOne which outputs a bit-perfect data stream via Digital Coaxial to the Schiit Modi Multibit DAC. This unit is powered by the iFi Audio iPower 5v PSU. (The best $49 spent on the Affordable Audiophile Reference system)
The second system uses the Raspberry Pi, again being fed the data via Ethernet, and converted to an Audio signal with the Allo Boss DAC.
In either application, the exposure to RF noise is limited.
I am using a complete set of HFC Magnetic Adapters on the coaxial, and both ends of the RCA interconnects to my receiver.
No USB equals, no USB noise.
https://www.facebook.com/AffordableAudiophile