Yes. I did various comparisons. I had one 300.1 and one 200, and my speakers are Avalon Ascent II.
Listening to them in Mono (one speaker only) the 300 was warmer, richer and more forgiving of sibilance. The 200 was more detailed and vivid.
Then I used them as (asymmetrical) monoblocks, adjusting the higher gain of the 300 with its controller. This produced the deepest holographic soundstage I have ever heard with a gorgeous textured base. This must be close to what 2 300's as monoblocks must be like ?!!?
Fplanner2010 the difference between a 300.1 and Cognac is that the 300.1 does not give you a headache.