I moved my system to the sidewall years ago, HUGE difference... Open up the soundstage, kill a lot of direct vibration, and honestly looks and operates much more ergonomically.
The downside, longer cables, but if you go XLR from preamp to amp in the middle of the speakers, or even better now in my opinion after years of experimenting and just changing over a friends system to this configuration, believe it or not good 20 ft, or 25 ft speaker cables of at least 12 gauge to 9 gauge really sound no different from when I had 2ft of the same cable from mono blocks with the system in the middle of the system.
The offset of having the components )especially analog gear and table) on the side is worth the long speaker cables for sure if you have a room you can pull it off in.