Well I did it and despite warnings of doom, the results were fantastic. I had my Scott 222 worked on by Ryan at http://www.hotglassaudio.com/. Like Craig at Nosvalves, Ryan uses the right kind of replacement parts and his whole approach is to get the amp back to its original design specs. From what I could tell, this guy knows just about everything there is to know about old tube audio. Highly recommended.
Thanks to Ryan I now know that I have a somewhat rare 222 (just 222, not an A, B, C...). He said the 222 is biased very close to class A and is one of the best sounding Scotts. He replaced all the caps and other parts. Turned out someone replaced the power transformer and tried to disguise it as being the original part. Ryan said the replacement wasn't outputting enough voltage so he set me up with a new power transformer that he likes to use. All that and a few new tubes is all that was needed.
So, how does it sound? Fantastic and very much improved. I cannot do the whole audiophile sound description thing (liquid midrange with lushness in the upper...), but in a nutshell it sounds cleaner, brighter and crisper yet lost none of the warmth that I liked so much about this amp. Is the Scott the best amp of all time? Of course not, but even though the price of a used Scott is going up a bit you could buy one, have it restored by someone who knows their stuff, and you will end up with a Jolida or Prima Luna beater at half the price.