can both balanced and unbalanced be used a once?

Mixing two different amps even from the same manufacturer can be tricky business. While it's possible that different out puts could compensate for it, it's much more likely that it's going to further complicate things. Might be worth considering replacing your amps with something more manageble.

I have a Classe 30 (currently sitting in the box, because of upgrading), and I used the balanced and unbalanced out at the same time for several years -- balanced to drive the main power amp, and unbalanced to drive a powered subwoofer. I experienced no problems whatsoever, though eventually the upgrade bug bit. It is true that you will likely have an issue with balance between the amps, though, if neither has level controls. Another option, which I also used with the Classe 30, is to split the unbalanced output using y-connectors (I used some nice heavy goldplated ones sold for car audio); then both amps are getting the same signal. I'm sure the same thing would work with the balanced outs if you can find or make the appropriate y-adapters. Anyway, I agree that you won't hurt any of the gear by trying it. Good luck!

I use balanced and unbalanced outputs to power one system in my office and the other in my living room. As many above have stated you will encounter problems using them in the same room. It might not be worth it.

One thing not to do: try and get fancy and use balanced and unbalanced inputs on the same amp at the same time, using the switch to go back-and-forth from one source to another.

Many amps double-up circuits and simply moving the switch back and forth will not isolate the systems.

Thanks for all the comments guys. It gives me some clarity on the various issues involved and possible options. From the sound of it no harm would be done by experimenting with using both sets of preamp outs simultaneously. Whether it will be beneficial, we shall see.

I emailed the manufacturer on this topic after hearing from a few of you as well and will let you know what they have to say.

You will find Classe' customer service to be very responsive.