Blown Fuse

HI, If this is a tube amp, you could pull the tubes and see if it still blows the fuse. If not, get some new tubes. Power tubes tend to arc and blow fuses, but I would go ahead and get a complete set. Sometimes you can see which tube it is by a bright flash of light inside the tube just before the fuse blows.
If it is a solid state amp, or if it still blows the fuse with the tubes out, it probably has a short in the power supply or output stage, such as a rectifier or capacitor. You will need to take in for service.

Before some further damage is done, I would have a professional check it out. That will minimize damage and cost.

I agree with Lak usually a repeated blown fuse means an actual problem and should have a professional opinion. After all you do not want a serious problem with your equipment so take care of it now, IMO.