Long distance from amp to speakers

Balanced wires would be great for your situation if your gear can accomidate them, long runs are the reason those cables exist.

Unless you really want to screw up the synergy to your system I would NOT run long speaker cables across the room. Have you tried the I'll just shut the system down since you won't let me use it the way it was supposed to be setup? I'm not trying to flame on you and I wish you luck. I just don't understand spending thousands (I meant to say hundreds of dollars) in case your wife is looking over your shoulder and reading this on equipment and then setting it up at home in a substandard way? I'm so glad I did get divorced 5 years ago. Looking back now my ex wife even teased me and said "now you can set up the room the way you want to"! It's a control thing. Ask her to at least compromise. They can only withhold sex for so long anyway.

The other thing you can do is place the amp next to the speakers and have your preamp on the other side of the room and run a long balanced interconnect?