It could work IF: The amp has great transformers and a strong power supply and you don't play the music much above 80db. Not all SET's are created equal.
I've heard 100 watt amps take a dump trying to drive my 3.6's. Even at lower levels it sounded anemic. My Bedini, at 45 watts, does fine. I also use an SET sometimes. It's an Art Audio Carissa Sig with 16 watts. It works great within its limits. Most people I have demoed my system for have preferred the Carissa to the others, of course, within its limits.
I've heard 100 watt amps take a dump trying to drive my 3.6's. Even at lower levels it sounded anemic. My Bedini, at 45 watts, does fine. I also use an SET sometimes. It's an Art Audio Carissa Sig with 16 watts. It works great within its limits. Most people I have demoed my system for have preferred the Carissa to the others, of course, within its limits.