Which speakers will fill 5,000 cubic ft coherently

Having spoken to some people whom I greatly respect, I have added the Coincident line to my final few as well as Duke's Jazz Module; I would look for a Total Eclipse, but they are not available on A'gon, but the Total Reference is. Zu Defintions remain high up, but I don't seem to get a handle on their sound, other than the 6 Moons review, which is more akin to a racing car review:) Any views on the Total Reference? I suppose ideally, with an amp such as the A-S MA 2.2, it seems redundant to have a built in sub amp (the Zu)which is unlikely to be as good as the A-S amp. So a full-range speaker without a sub amp would seem to be the theoretical ideal and so far only the Coincident seems to fit the entire bill. But can they be placed close to the front wall?

The most recent reviews of Def 2s are in Positive-Feedback and HiFi+

Nothing will do better than the Beveridge model 3. they are perfect for this type application.

"I suppose ideally, with an amp such as the A-S MA 2.2, it seems redundant to have a built in sub amp (the Zu)which is unlikely to be as good as the A-S amp. So a full-range speaker without a sub amp would seem to be the theoretical ideal and so far only the Coincident seems to fit the entire bill."

Despite the fevered claims of some tubaholics, there is a definite advantage to be had by using tubes above 50 Hz and solid stste below that point. There is some discussion afoot about whether newer class D designs outperform the conventional A and A/B amplifiers but very few would argue that tubes provide better bass reproduction than SS can.
Furthermore, it is certain that splitting low bass duties out of the main amplfier's assignment will improve it's ability to control the mids. That's why statement products are often multi-amped and/or actively powered.