Eldartford, is this a test? Sorry, but as near as I can determine, a fuse can be used at any voltage below its rating.
In the 'hydraulic' model, volts is pressure and amps is a quantity....somewhat independent.
If your contention were true, the fuse would provide little or no protection, since you could somehow devise an amplifier which would output very low voltage @ very hi current, and still be within your definition of a fuses ratings.
A fuse doesn't dissipate 'watts'...
My bad with my first post was poor choice of numbers.
I still maintain that hi-current to maggies is somewhat of a red-herring.
Please design a scenario where a maggie can receive say...20 amps at whatever voltage you choose. Than, find me an amp that produces such and not 'pop' the fuse.
Also, with the voltage rails at +- a (given) voltage, this represents the maximum voltage the speakers can see. The absolute value of +-50 volts is 100v Without Sign. (absolute value definition)
The only thing left to argue about is 'how large a spike a fuse can take over what time period'
http://www.circuitprotection.ca/fuseology.html#Top
Link has useful chart and definitions. Go to the bottom of the page and look at 'Voltage Ratings'...that a 250v fuse can safely be used in a 125v circuit negates your arguement.