That makes three of us. If you don't have a good source and amplification chain, you can't pick the right speakers for your room.
IMO, speakers are very personal and have the most variability in sound. Or put another way, there are more trade-offs to be made at the speaker level than the electronics level. So nail the front end, based on reviews, listening tests, friends systems, etc. You'll likely get much closer to a sound you like for a long time than with speakers.
Of course, be sure to take a systems approach and no matter what you spend for your speakers make sure the impedance and sensitivity match the electronics.