My system consists of of a DIY tube preamp with beefy power supply, the amps mentioned above, Luxman DA06 dac and PS Audio memory player transport. All my wire is Western Electric NOS from the 70s. Thick gauge for the power cords and speaker wire .. 10 ga.
This is system has zero fatigue and has me forgetting completely about how this or that part of the system sounds. The music, in totality, just sounds right. Very nice end result. The speakers are the main reason. They are not the most resolving. They are not the most extended in the top end. Other speakers image better...and do other aphile tricks better. However no speaker I have heard plays music with more simply enjoyment.
The he one exception may be the Soundlab M1 speakers I owned. The two sound very much alike really. The SLs are huge however and need tons of power.