Has anyone found Audio Nirvana?

i think slowhand's got it just right. the set-up that helps the audio entheusiast in me cross over with the music lover in me (with fairly impressive frequency): wadia's 850 driven by a pair of cj prem. 12's through jm labs' mezzo utopias. wired with transparent reference speaker & kcag interconnects. simple, synergistic and fun.

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I've found it several times since 1975.

I'll probably find it a few more times before I'm done.

Kinda like getting married.  You find her, sincerely with all your heart tell the world that you will be together til death do you part.  You divorce, find her again and profess your love til death do you part...repeat, repeat....
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For me, yes. It all begins w/ my speakers- Thiel CS 2.4SE.
I will carefully build the rest of my rig around them.

After 25 long years, I feel pretty close with CEC Transport, Direct Heated Triode Dac, Tube Research Labs Preamp, NuForce Ref9 V2 SE Amps, Intuitive Design Summit Speakers.

You cannot attain audio nirvana Grasshopper, but you can get close.