I would add IF the contact between the fuse end caps and fuse holder clip/s contact/s are such that a VD can be measured (From fuse clip to fuse clip) then what else can/is going on in the poor connection? Maybe an ever so slight arcing between the fuse end cap/s and the fuse holder clip/s? If the fuse holder in mounted directly to the circuit board in close proximity of electronic components who can say if the ever so slight arcing can be sending/spewing out RFI infecting the electronics? Who can say if the arcing is causing a vibration on the circuit board? Is there is energy being created by the ever so light arcing? What impact might the energy create by the arcing have on the electronics of the piece of equipment.
Like atmashere said in an earlier post his preamp’s power suppliers are regulated so a small AC Line mains VD would not have any impact on the SQ of the preamp. But what if the connection between the fuse end caps and fuse clip/s was such that a VD existed, therefore maybe, an ever so small arcing was happening. So, what IF?
Jmho, the differences heard in SQ is not from minuscule resistance of the fuse element inside the fuse that measures higher in one direction than the other, which is said to create a minuscule VD across the fuse element, measured in a live completed circuit from fuse end cap to end cap.