Hi fjn04,
Initially, I don’t see any issues, using the Oppo as a control center will send video to the plasma and sound to the speakers from anything connected to it, but a couple of questions just to be sure.
1) Since you are currently using Blu-ray, I assumed the plasma has an HDMI input, or at least a DVI using an adapter.
2) What other sources (cable box, etc.) will you be using and can I assume they have HDMI output?
3) How do you stream Netflix? Cable box, Apple TV, Chromecast, or Roku?
4) Once the system is in place will you use it 100% of the time or do you need the ability to just use the plasma only?