Should work. Very similar to what I am doing. Only thing to keep in mind is that if you apply cross over to your mains in the meridian in MCH mode, AND you run a set of outputs from your preamp (I presume with HT bypass) through the NHT, you will get low pass information from your mains twice.
First on the LFE channel (crossed over in the Meridian), and once more from the stereo inputs in the NHT. This is certainly the case if you cross over in the Meridian while still running the mains at full range. But even if you apply a high pass filter to the mains in the Meridian, quite a bit of LF information will still be there (because of the slope of the filter) for the NHT to send to the subs (adding it to the LFE channel information).
The way around this would be to not use the Meridian crossover for the mains, but let the NHT do the work through the stereo inputs, even in MCH mode.
First on the LFE channel (crossed over in the Meridian), and once more from the stereo inputs in the NHT. This is certainly the case if you cross over in the Meridian while still running the mains at full range. But even if you apply a high pass filter to the mains in the Meridian, quite a bit of LF information will still be there (because of the slope of the filter) for the NHT to send to the subs (adding it to the LFE channel information).
The way around this would be to not use the Meridian crossover for the mains, but let the NHT do the work through the stereo inputs, even in MCH mode.