Sure, the Wywires are ever so slightly smoother on the top end, not rolled off just more pleasing especially on cymbals for example. I would call it more refined. Maybe copper versus a mixed alloy? They are also a little warmer than Venustas in the upper bass and lower midrange region that is more enjoyable, in my system at least. I would call both musical cables, but more refinement with the WW. The Wywires IC's I have were Alex's first endeavor when he offered only 1 model. He actually designed the first pair for my Thiel 3.6's which are reputed by some to have a hot tweeter, I own 2 models and have used Thiels for 20 years so I disagree. They are just ultra transparent and must be matched upstream with components that have a tonality you want the Thiels to reveal.
I did have a pair of Eggleston Andra II's for a while (kept both Thiels) so I talked to Alex about another pair, he designed those with a little more air than the first pair due to the slightly dark character of the Eggy's. With both pair in the path I found them too warm with the Eggy's, the Venustas was better in this case. I ended up selling the Eggy's, they were just way too different than the Thiels, could never really get them to open up, with either Mcintosh or Classe amps.
Waxwaves as you and I both know cables are so system dependent. I have a very revealing analog front end and utter transparancy on the back end and the Wywires are in the musical camp, a great fit. I also use his first PC, the Juice, on both amps and my preamp. They offer the same refinement as the IC's and a lower noise floor. No frequency is over emphasized which happens with so many other PC's.
I have had success with other cables but right now the Wywires are doing the trick. I have never tried his speaker cables. I keep a lot of cables I buy and the Venustas will always either be in they system or on the bench. I have not tried any of Alex's other models.
