The E-350 is a very well built integrated, you gain a lot of feature like pre-out/main-in, bypassable tone control and headphone output, it also has slots for D/A and phono card. If you can find one with good price and condition, I will say go for it, try it in your system, if you don't like it, you should have no problem to resell it. BTW, my experience with Accuphase is their pure class A amp is more sweet sounding.
If you want something more sweet and warm, tube amp is the answer.