Sure, but as I alluded to, its not in the audio (more specifically analog vs digital) world. I wasn't trying to take subject matter beyond the interest in audio. However in the RF (now we are out realm of "wired" interests) world, where one is interested in "using" low power RF signals emitted in free-space, there are numerous instances where directionality is impacted by material construction (type of insulation; Teflon being but one good example), type of conductor (Silver plated copper, and in some instances pure silver- silver is a better conductor than copper), terminations, etc. and all are considered to reduce transmission losses (insertion losses), and maintain gain when you have exploited all that's possible from things like antenna gain, pattern coverage, etc. However, one is dealing with signals that are much lower in emitted power than normally seen in low-power level signals from your phono player, CD, Preamp, etc. Often one is also dealing with frequencies that are in the GHz bands, not KHz as with audio. However, none of this is fair nor applicable to the subject at hand. Frankly the benefits of such wiring just isn't cost effective with audio signals. However, that doesn't mean its not used to help sell lots of signal IC and speaker cables.
However, I'm sure that geoffkait can well appreciate some of this since he is totally wireless anyway. I'm still working on my wireless approach, but alas its limited to Blue Tooth and WiFi as well as 2.4 & 5.6 GHz home networking products. I'm still researching Nickola Tesla's work in wireless power transmission to see if I can build my own Wardenclyffe Tower, but my homeowners covenants prevent having one as tall as Tesla had.